MolNFT v1 · #33361 · protein
Crystal structure of dimethylarginine dimethylaminohydrolase I in complex with zinc, high pH
2CI7 · Ng, ng-dimethylarginine dimethylaminohydrolase 1: “Crystal structure of dimethylarginine dimethylaminohydrolase I in complex with zinc, high pH”. X-ray diffraction, 2 ligands (GLY, ZN), 3 pockets (best druggability 0.81). MolNFT v1…
- PDB
- 2CI7
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ng, ng-dimethylarginine dimethylaminohydrolase 1
- EC
- 3.5.3.18
- UniProt
- P56965
- Ligands
- GLY, ZN
- Pockets
- 3 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ng, ng-dimethylarginine dimethylaminohydrolase 1 (EC 3.5.3.18) | protein | 273 | 32% helix, 26% strand | P56965 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 344 | 0.81 | 0.91 | 31 | empty |
| 2 | 78 | 0.35 | 0.76 | 18 | empty |
| 3 | 54 | 0.29 | 0.75 | 11 | empty |
Compared structures
- 2CI7 · Crystal structure of Dimethylarginine Dimethylaminohydrolase I in complex with Zinc, high… · the same entry in another collection · chain A against A, TM-score 1.00
- P56965 · AlphaFold monomer V2.0 prediction for N(G),N(G)-dimethylarginine dimethylaminohydrolase 1… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P56965
- Elsewhere: RCSB PDB 2CI7 · PDBe 2CI7 · UniProt P56965
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