MolNFT v1 · #32893 · protein

Structure of iodinated CBM25 from bacillus halodurans amylase

2C3V · Alpha-amylase G-6: “Structure of iodinated CBM25 from bacillus halodurans amylase”. X-ray diffraction, 1 ligand (IOD), 2 pockets (best druggability 0.53). MolNFT v1 #32893 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2C3V
Type: protein
Length: 188 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-amylase G-6
UniProt: Q9KFR4
Ligands: IOD
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-amylase G-6	protein	94	3% helix, 49% strand	Q9KFR4
B	Alpha-amylase G-6	protein	94	3% helix, 48% strand	Q9KFR4

Ligands and binding sites

IOD · Iodide ion · ion · 3 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	232	0.53	0.77	31	empty
2	162	0.45	0.76	25	empty

Interfaces

1 interface between chains.

A–B · 355 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (nonstandard).

Compared structures

2C3V · Structure of iodinated CBM25 from Bacillus halodurans amylase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9KFR4
Elsewhere: RCSB PDB 2C3V · PDBe 2C3V · UniProt Q9KFR4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.