MolNFT v1 · #31964 · protein
T7-tagged full-length streptavidin
2BC3: “T7-tagged full-length streptavidin”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.42). MolNFT v1 #31964 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2BC3
- Type
- protein
- Length
- 286 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Streptavidin
- UniProt
- P22629
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.42
Structure
x-ray diffraction · 2 distinct chains · 14% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Streptavidin | protein | 145 | 15% helix, 46% strand | P22629 |
| B | Streptavidin | protein | 141 | 13% helix, 48% strand | P22629 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.42 | 0.74 | 29 | empty |
| 2 | 102 | 0.38 | 0.75 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 765 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 2BC3 · T7-tagged full-length streptavidin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22629
- Elsewhere: RCSB PDB 2BC3 · PDBe 2BC3 · UniProt P22629
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