MolNFT v1 · #31417 · protein

Unliganded hincii

2AUD · Type II restriction enzyme hincii: “Unliganded hincii”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #31417 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2AUD
Type: protein
Length: 242 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Type II restriction enzyme hincii
EC: 3.1.21.4
UniProt: P17743
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Type II restriction enzyme hincii (EC 3.1.21.4)	protein	242	40% helix, 19% strand	P17743

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	105	0.36	0.74	23	empty

Compared structures

2AUD · Unliganded HincII · the same entry in another collection · chain A against A, TM-score 1.00
P17743 · AlphaFold monomer V2.0 prediction for type-2 restriction enzyme hincii (P17743) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17743
Elsewhere: RCSB PDB 2AUD · PDBe 2AUD · UniProt P17743

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