UniProt P17743
Type-2 restriction enzyme hincii (P17743)
Type-2 restriction enzyme hincii (UniProt P17743): 14 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P17743
- Protein
- Type-2 restriction enzyme hincii
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
15 records of P17743 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KC6 | HincII Bound to Cognate DNA | x-ray diffraction | A, B, C, D | — | — |
| 1KC6 | Hincii bound to cognate DNA | x-ray diffraction | A, B, C, D | — | — |
| 1XHU | HincII bound to cleaved, cognate DNA containing GTCGAC | x-ray diffraction | A, B, C, D | — | — |
| 1XHU | Hincii bound to cleaved, cognate DNA containing gtcgac | x-ray diffraction | A, B, C, D | — | — |
| 1XHV | HincII bound to cleaved cognate DNA GTCGAC and Mn2+ | x-ray diffraction | A, B, C, D | — | — |
| 1XHV | Hincii bound to cleaved cognate DNA gtcgac and MN2+ | x-ray diffraction | A, B, C, D | — | — |
| 2AUD | Unliganded HincII | x-ray diffraction | A | — | — |
| 2AUD | Unliganded hincii | x-ray diffraction | A | — | — |
| 2GIH | Q138F HincII bound to cognate DNA GTCGAC and Ca2+ | x-ray diffraction | A, B | — | — |
| 2GIH | Q138F hincii bound to cognate DNA gtcgac and CA2+ | x-ray diffraction | A, B | — | — |
| 2GIJ | Q138F HincII bound to cognate DNA GTTAAC and Ca2+ | x-ray diffraction | A, B | — | — |
| 2GIJ | Q138F hincii bound to cognate DNA gttaac and CA2+ | x-ray diffraction | A, B | — | — |
| 3EBC | Structure of N141A HincII with Cognate DNA | x-ray diffraction | A, B | — | — |
| 3EBC | Structure of N141A hincii with cognate DNA | x-ray diffraction | A, B | — | — |
| P17743 | AlphaFold monomer V2.0 prediction for type-2 restriction enzyme hincii (P17743) | predicted | A | — | 1 (best 0.63) |
Experiment against prediction
- 3EBC chain A against the predicted model P17743: TM-score 0.99, RMSD 0.53 Å
- 3EBC chain A against the predicted model P17743: TM-score 0.99, RMSD 0.53 Å
- 1KC6 chain D against the predicted model P17743: TM-score 0.99, RMSD 0.55 Å
- 1KC6 chain D against the predicted model P17743: TM-score 0.99, RMSD 0.55 Å
- 1XHV chain D against the predicted model P17743: TM-score 0.99, RMSD 0.56 Å
- 1XHV chain D against the predicted model P17743: TM-score 0.99, RMSD 0.56 Å
- 1KC6 chain B against the predicted model P17743: TM-score 0.99, RMSD 0.57 Å
- 1KC6 chain B against the predicted model P17743: TM-score 0.99, RMSD 0.57 Å
- 2GIJ chain B against the predicted model P17743: TM-score 0.99, RMSD 0.59 Å
- 2GIJ chain B against the predicted model P17743: TM-score 0.99, RMSD 0.59 Å
Elsewhere
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