MolNFT v1 · #30971 · protein
Spry domain-containing socs box protein 2 (ssb-2)
2AFJ · Gene rich cluster, C9 gene: “Spry domain-containing socs box protein 2 (ssb-2)”. Solution nmr, 3 pockets (best druggability 0.62). MolNFT v1 #30971 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2AFJ
- Type
- protein
- Length
- 226 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Gene rich cluster, C9 gene
- UniProt
- O88838
- Pockets
- 3 · best druggability 0.62
Structure
solution nmr · 1 distinct chain · 10% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gene rich cluster, C9 gene | protein | 226 | 10% helix, 22% strand | O88838 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 211 | 0.62 | 0.82 | 31 | empty |
| 2 | 132 | 0.53 | 0.81 | 26 | empty |
| 3 | 52 | 0.28 | 0.75 | 14 | empty |
Compared structures
- 2AFJ · SPRY domain-containing SOCS box protein 2 (SSB-2) · the same entry in another collection · chain A against A, TM-score 1.00
- O88838 · AlphaFold monomer V2.0 prediction for spry domain-containing socs box protein 2 (O88838) · a predicted model of the same protein · chain A against A, TM-score 0.41
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88838
- Elsewhere: RCSB PDB 2AFJ · PDBe 2AFJ · UniProt O88838
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