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Spry domain-containing socs box protein 2 (ssb-2)

Analyse Spry domain-containing socs box protein 2 (ssb-2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2AFJ
Type
protein
Length
226 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Gene rich cluster, C9 gene
UniProt
O88838
Pockets
3 · best druggability 0.62

Structure

solution nmr · 1 distinct chain · 10% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGene rich cluster, C9 geneprotein22610% helix, 22% strandO88838

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12110.620.8231empty
21320.530.8126empty
3520.280.7514empty

Compared structures

  • 2AFJ · SPRY domain-containing SOCS box protein 2 (SSB-2) · the same entry in another collection · chain A against A, TM-score 1.00
  • O88838 · AlphaFold monomer V2.0 prediction for spry domain-containing socs box protein 2 (O88838) · a predicted model of the same protein · chain A against A, TM-score 0.41

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