MolNFT v1 · #30964 · protein
X-ray crystal structure of protein Q8A8B0 from bacteroides thetaiotaomicron. northeast structural genomics consortium target BTR9.
2AFC · Conserved hypothetical protein: “X-ray crystal structure of protein Q8A8B0 from bacteroides thetaiotaomicron. northeast structural genomics…”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #30964 on GenesisL1: 3D…
- PDB
- 2AFC
- Type
- protein
- Length
- 306 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein
- UniProt
- Q8A8B0
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Conserved hypothetical protein | protein | 153 | 33% helix, 27% strand | Q8A8B0 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 204 | 0.53 | 0.77 | 28 | empty |
| 2 | 183 | 0.52 | 0.78 | 21 | empty |
| 3 | 73 | 0.33 | 0.75 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 880 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 2AFC · X-Ray Crystal Structure of Protein Q8A8B0 from Bacteroides thetaiotaomicron. Northeast… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A8B0
- Elsewhere: RCSB PDB 2AFC · PDBe 2AFC · UniProt Q8A8B0
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