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X-ray crystal structure of protein Q8A8B0 from bacteroides thetaiotaomicron. northeast structural genomics consortium target BTR9.

Analyse X-ray crystal structure of protein Q8A8B0 from bacteroides thetaiotaomicron.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2AFC
Type: protein
Length: 306 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved hypothetical protein
UniProt: Q8A8B0
Pockets: 3 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Conserved hypothetical protein	protein	153	33% helix, 27% strand	Q8A8B0

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	204	0.53	0.77	28	empty
2	183	0.52	0.78	21	empty
3	73	0.33	0.75	11	empty

Interfaces

1 interface between chains.

A–B · 880 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

2AFC · X-Ray Crystal Structure of Protein Q8A8B0 from Bacteroides thetaiotaomicron. Northeast… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8A8B0
Elsewhere: RCSB PDB 2AFC · PDBe 2AFC · UniProt Q8A8B0

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