MolNFT v1 · #30807 · protein
Epsp synthase liganded with shikimate
2AA9 · 3-phosphoshikimate 1-carboxyvinyltransferase: “Epsp synthase liganded with shikimate”. X-ray diffraction, 1 ligand (SKM), 3 pockets (best druggability 0.72). MolNFT v1 #30807 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2AA9
- Type
- protein
- Length
- 427 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-phosphoshikimate 1-carboxyvinyltransferase
- EC
- 2.5.1.19
- UniProt
- P0A6D3
- Ligands
- SKM
- Pockets
- 3 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) | protein | 427 | 36% helix, 26% strand | P0A6D3 |
Ligands and binding sites
- SKM · (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylic acid · ligand · chains A
- FMT · Formic acid · additive · 17 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 67 | 0.72 | 0.98 | 26 | SKM, FMT |
| 2 | 73 | 0.33 | 0.75 | 15 | empty |
| 3 | 54 | 0.30 | 0.76 | 18 | FMT |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A6D3
- Elsewhere: RCSB PDB 2AA9 · PDBe 2AA9 · UniProt P0A6D3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.