MolNFT v1 · #30689 · protein
Structure solution to 2.2 ångström and functional characterisation of the open reading frame RV3214 from mycobacterium tuberculosis
2A6P · Possible phosphoglycerate mutase GPM2: “Structure solution to 2.2 ångström and functional characterisation of the open reading frame RV3214 from…”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.73). MolNFT v1…
- PDB
- 2A6P
- Type
- protein
- Length
- 386 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Possible phosphoglycerate mutase GPM2
- EC
- 5.4.2.1
- UniProt
- Q6MWZ7
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Possible phosphoglycerate mutase GPM2 (EC 5.4.2.1) | protein | 193 | 40% helix, 20% strand | Q6MWZ7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 692 | 0.73 | 0.79 | 94 | SO4, GOL |
Interfaces
1 interface between chains.
- A–B · 1026 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 2A6P · Structure Solution to 2.2 Angstrom and Functional Characterisation of the Open Reading… · the same entry in another collection · chain A against A, TM-score 1.00
- Q6MWZ7 · AlphaFold monomer V2.0 prediction for acid phosphatase (Q6MWZ7) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6MWZ7
- Elsewhere: RCSB PDB 2A6P · PDBe 2A6P · UniProt Q6MWZ7
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