Research workbench
Structure solution to 2.2 ångström and functional characterisation of the open reading frame RV3214 from mycobacterium tuberculosis
Analyse Structure solution to 2.2 ångström and functional characterisation of the open… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2A6P
- Type
- protein
- Length
- 386 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Possible phosphoglycerate mutase GPM2
- EC
- 5.4.2.1
- UniProt
- Q6MWZ7
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Possible phosphoglycerate mutase GPM2 (EC 5.4.2.1) | protein | 193 | 40% helix, 20% strand | Q6MWZ7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 692 | 0.73 | 0.79 | 94 | SO4, GOL |
Interfaces
1 interface between chains.
- A–B · 1026 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 2A6P · Structure Solution to 2.2 Angstrom and Functional Characterisation of the Open Reading… · the same entry in another collection · chain A against A, TM-score 1.00
- Q6MWZ7 · AlphaFold monomer V2.0 prediction for acid phosphatase (Q6MWZ7) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6MWZ7
- Elsewhere: RCSB PDB 2A6P · PDBe 2A6P · UniProt Q6MWZ7
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