MolNFT v1 · #29359 · protein

Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S

1Z6C: “Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S”. Solution nmr, 1 ligand (CA), 1 pocket (best druggability 0.33). MolNFT v1 #29359 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1Z6C
Type: protein
Length: 87 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vitamin K-dependent protein S
UniProt: P07225
Ligands: CA
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 5% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vitamin K-dependent protein S	protein	87	5% helix, 17% strand	P07225

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.33	0.76	18	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1Z6C · Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S · the same entry in another collection · chain A against A, TM-score 1.00
P07225 · AlphaFold monomer V2.0 prediction for vitamin K-dependent protein S (P07225) · a predicted model of the same protein · chain A against A, TM-score 0.46

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07225
Elsewhere: RCSB PDB 1Z6C · PDBe 1Z6C · UniProt P07225

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