MolNFT v1 · #29283 · protein

Angiopoietin-2 receptor binding domain

1Z3S: “Angiopoietin-2 receptor binding domain”. X-ray diffraction, 1 ligand (CA). MolNFT v1 #29283 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1Z3S
Type: protein
Length: 432 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Angiopoietin-2
UniProt: O15123
Ligands: CA

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Angiopoietin-2	protein	216	15% helix, 30% strand	O15123

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1Z3S · Angiopoietin-2 Receptor Binding Domain · the same entry in another collection · chain A against A, TM-score 1.00
O15123 · AlphaFold monomer V2.0 prediction for angiopoietin-2 (O15123) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O15123
Elsewhere: RCSB PDB 1Z3S · PDBe 1Z3S · UniProt O15123

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