MolNFT v1 · #29227 · protein

GDP-bound RAB23 GTPase crystallized in C222(1) space group

1Z22 · RAS-related protein rab-23: “GDP-bound RAB23 GTPase crystallized in C222(1) space group”. X-ray diffraction, 2 ligands (GDP, MG), 1 pocket (best druggability 0.38). MolNFT v1 #29227 on GenesisL1: 3D structure, binding sites and…

PDB: 1Z22
Type: protein
Length: 164 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RAS-related protein rab-23
UniProt: P35288
Ligands: GDP, MG
Pockets: 1 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAS-related protein rab-23	protein	164	38% helix, 26% strand	P35288

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	93	0.38	0.76	20	empty

Compared structures

1Z22 · GDP-Bound Rab23 GTPase crystallized in C222(1) space group · the same entry in another collection · chain A against A, TM-score 1.00
P35288 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-23 (P35288) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35288
Elsewhere: RCSB PDB 1Z22 · PDBe 1Z22 · UniProt P35288

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