MolNFT v1 · #29166 · protein
Crystal structure of the rok family transcriptional regulator, homolog of E.COLI mlc protein.
1Z05 · Transcriptional regulator, rok family: “Crystal structure of the rok family transcriptional regulator, homolog of E.COLI mlc protein.”. X-ray diffraction, 2 ligands (ZN, SO4), 3 pockets (best druggability 0.65). MolNFT v1 #29166 on…
- PDB
- 1Z05
- Type
- protein
- Length
- 396 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, rok family
- UniProt
- Q9KQJ1
- Ligands
- ZN, SO4
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, rok family | protein | 396 | 45% helix, 22% strand | Q9KQJ1 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
- SO4 · Sulfate ion · ion · 6 copies · chains A
- BME · Beta-mercaptoethanol · additive · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 348 | 0.65 | 0.80 | 47 | SO4 |
| 2 | 199 | 0.50 | 0.76 | 18 | empty |
| 3 | 58 | 0.27 | 0.73 | 18 | empty |
Modifications
Observed in the structure: 1 covalent (additive adduct).
Compared structures
- 1Z05 · Crystal structure of the ROK family transcriptional regulator, homolog of E.coli MLC… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9KQJ1
- Elsewhere: RCSB PDB 1Z05 · PDBe 1Z05 · UniProt Q9KQJ1
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