Research workbench
Crystal structure of the rok family transcriptional regulator, homolog of E.COLI mlc protein.
Analyse Crystal structure of the rok family transcriptional regulator, homolog of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1Z05
- Type
- protein
- Length
- 396 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, rok family
- UniProt
- Q9KQJ1
- Ligands
- ZN, SO4
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, rok family | protein | 396 | 45% helix, 22% strand | Q9KQJ1 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
- SO4 · Sulfate ion · ion · 6 copies · chains A
- BME · Beta-mercaptoethanol · additive · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 348 | 0.65 | 0.80 | 47 | SO4 |
| 2 | 199 | 0.50 | 0.76 | 18 | empty |
| 3 | 58 | 0.27 | 0.73 | 18 | empty |
Modifications
Observed in the structure: 1 covalent (additive adduct).
Compared structures
- 1Z05 · Crystal structure of the ROK family transcriptional regulator, homolog of E.coli MLC… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9KQJ1
- Elsewhere: RCSB PDB 1Z05 · PDBe 1Z05 · UniProt Q9KQJ1
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