MolNFT v1 · #28876 · protein
The C2 domain of PKC<DELTA> is a new phospho-tyrosine binding domain
1YRK · Protein kinase C, delta type: “The C2 domain of PKC<DELTA> is a new phospho-tyrosine binding domain”. X-ray diffraction. MolNFT v1 #28876 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1YRK
- Type
- protein
- Length
- 139 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein kinase C, delta type; 13-residue peptide
- UniProt
- Q05655
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein kinase C, delta type | protein | 126 | 7% helix, 55% strand | Q05655 |
| B | 13-residue peptide | protein | 13 | 0% helix, 8% strand | — |
Ligands and binding sites
- ACY · Acetic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 695 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1YRK · The C2 Domain of PKC<delta> is a new Phospho-Tyrosine Binding Domain · the same entry in another collection · chain A against A, TM-score 1.00
- Q05655 · AlphaFold monomer V2.0 prediction for protein kinase C delta type (Q05655) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q05655
- Elsewhere: RCSB PDB 1YRK · PDBe 1YRK · UniProt Q05655
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