MolNFT v1 · #28821 · protein

Crystal structure of vaccinia virus L1 protein

1YPY · Virion membrane protein: “Crystal structure of vaccinia virus L1 protein”. X-ray diffraction, 8 pockets (best druggability 0.78). MolNFT v1 #28821 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YPY
Type: protein
Length: 350 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Virion membrane protein
UniProt: P07612
Pockets: 8 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Virion membrane protein	protein	182	48% helix, 24% strand	P07612
B	Virion membrane protein	protein	168	51% helix, 22% strand	P07612

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	217	0.78	0.91	29	empty
2	201	0.73	0.89	24	empty
3	63	0.61	0.91	15	empty
4	64	0.58	0.89	17	empty
5	58	0.57	0.90	22	empty

Interfaces

1 interface between chains.

A–B · 573 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1YPY · Crystal Structure of Vaccinia Virus L1 protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07612
Elsewhere: RCSB PDB 1YPY · PDBe 1YPY · UniProt P07612

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.