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Crystal structure of vaccinia virus L1 protein
Analyse Crystal structure of vaccinia virus L1 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YPY
- Type
- protein
- Length
- 350 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Virion membrane protein
- UniProt
- P07612
- Pockets
- 8 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Virion membrane protein | protein | 182 | 48% helix, 24% strand | P07612 |
| B | Virion membrane protein | protein | 168 | 51% helix, 22% strand | P07612 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 217 | 0.78 | 0.91 | 29 | empty |
| 2 | 201 | 0.73 | 0.89 | 24 | empty |
| 3 | 63 | 0.61 | 0.91 | 15 | empty |
| 4 | 64 | 0.58 | 0.89 | 17 | empty |
| 5 | 58 | 0.57 | 0.90 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 573 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 1YPY · Crystal Structure of Vaccinia Virus L1 protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07612
- Elsewhere: RCSB PDB 1YPY · PDBe 1YPY · UniProt P07612
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