MolNFT v1 · #28679 · protein
Crystal structure of the conserved protein of unknown function PA5104 from pseudomonas aeruginosa PAO1
1YLL · Conserved hypothetical protein: “Crystal structure of the conserved protein of unknown function PA5104 from pseudomonas aeruginosa PAO1”. X-ray diffraction, 9 pockets (best druggability 0.77). MolNFT v1 #28679 on GenesisL1: 3D…
- PDB
- 1YLL
- Type
- protein
- Length
- 768 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein
- UniProt
- Q9HU79
- Pockets
- 9 · best druggability 0.77
Structure
x-ray diffraction · 4 distinct chains · 2% helix, 62% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Conserved hypothetical protein | protein | 190 | 3% helix, 63% strand | Q9HU79 |
| B | Conserved hypothetical protein | protein | 189 | 2% helix, 62% strand | Q9HU79 |
| C | Conserved hypothetical protein | protein | 194 | 2% helix, 62% strand | Q9HU79 |
| D | Conserved hypothetical protein | protein | 195 | 3% helix, 61% strand | Q9HU79 |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 96 | 0.77 | 0.98 | 18 | empty |
| 2 | 76 | 0.74 | 0.98 | 18 | empty |
| 3 | 685 | 0.72 | 0.79 | 66 | empty |
| 4 | 615 | 0.70 | 0.78 | 72 | empty |
| 5 | 149 | 0.58 | 0.83 | 25 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1021 Ų buried · 25 hydrogen bonds · protein-protein
- C–D · 1005 Ų buried · 22 hydrogen bonds · protein-protein
- A–D · 107 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 106 Ų buried · 1 hydrogen bond · protein-protein
- B–D · 70 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 1YLL · Crystal Structure of the Conserved Protein of Unknown Function PA5104 from Pseudomonas… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HU79
- Elsewhere: RCSB PDB 1YLL · PDBe 1YLL · UniProt Q9HU79
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