MolNFT v1 · #28654 · protein

Crystal structure of yellow fever virus NS3 helicase

1YKS · Genome polyprotein [contains: flavivirin protease NS3…: “Crystal structure of yellow fever virus NS3 helicase”. X-ray diffraction, 3 pockets (best druggability 0.78). MolNFT v1 #28654 on GenesisL1: 3D structure, binding sites and…

PDB: 1YKS
Type: protein
Length: 431 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Genome polyprotein [contains: flavivirin protease NS3 catalytic subunit]
EC: 3.4.21.91
UniProt: P19901
Pockets: 3 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Genome polyprotein [contains: flavivirin protease NS3 catalytic subunit] (EC 3.4.21.91)	protein	431	31% helix, 19% strand	P19901

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	961	0.78	0.80	95	empty
2	170	0.59	0.83	38	empty
3	56	0.31	0.76	16	empty

Compared structures

1YKS · Crystal structure of yellow fever virus NS3 helicase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19901
Elsewhere: RCSB PDB 1YKS · PDBe 1YKS · UniProt P19901

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