MolNFT v1 · #28450 · protein

Conserved hypothetical protein pfu-838710-001 from pyrococcus furiosus

1YEM: “Conserved hypothetical protein pfu-838710-001 from pyrococcus furiosus”. X-ray diffraction, 2 ligands (PT, UNX), 2 pockets (best druggability 0.67). MolNFT v1 #28450 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YEM
Type: protein
Length: 329 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved hypothetical protein pfu-838710-001
UniProt: Q8U2H2
Ligands: PT, UNX
Pockets: 2 · best druggability 0.67

Structure

x-ray diffraction · 2 distinct chains · 26% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Conserved hypothetical protein pfu-838710-001	protein	163	22% helix, 48% strand	Q8U2H2
B	Conserved hypothetical protein pfu-838710-001	protein	166	29% helix, 48% strand	Q8U2H2

Ligands and binding sites

PT · Platinum (II) ion · metal · chains A
UNX · Unknown atom or ion · ion · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	301	0.67	0.82	45	UNX
2	237	0.62	0.81	39	UNX

Interfaces

1 interface between chains.

A–B · 920 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

1YEM · Conserved hypothetical protein Pfu-838710-001 from Pyrococcus furiosus · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8U2H2
Elsewhere: RCSB PDB 1YEM · PDBe 1YEM · UniProt Q8U2H2

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