MolNFT v1 · #27808 · protein
Crystal structure of sialic acid synthase (neub) in complex with MN2+ and malate from neisseria meningitidis
1XUU · Polysialic acid capsule biosynthesis protein siac: “Crystal structure of sialic acid synthase (neub) in complex with MN2+ and malate from neisseria meningitidis”. X-ray diffraction, 2 ligands (MLT, MN), 1 pocket (best druggability…
- PDB
- 1XUU
- Type
- protein
- Length
- 348 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Polysialic acid capsule biosynthesis protein siac
- UniProt
- Q57265
- Ligands
- MLT, MN
- Pockets
- 1 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polysialic acid capsule biosynthesis protein siac | protein | 348 | 40% helix, 19% strand | Q57265 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 278 | 0.63 | 0.80 | 32 | MLT |
Compared structures
- 1XUU · Crystal structure of sialic acid synthase (NeuB) in complex with Mn2+ and Malate from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57265
- Elsewhere: RCSB PDB 1XUU · PDBe 1XUU · UniProt Q57265
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