MolNFT v1 · #27670 · protein
Crystal structure of native pa-agog, 8-oxoguanine DNA glycosylase from pyrobaculum aerophilum
1XQO: “Crystal structure of native pa-agog, 8-oxoguanine DNA glycosylase from pyrobaculum aerophilum”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #27670 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1XQO
- Type
- protein
- Length
- 253 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 8-oxoguanine DNA glycosylase
- UniProt
- Q8ZVK6
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 8-oxoguanine DNA glycosylase | protein | 253 | 64% helix, 0% strand | Q8ZVK6 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 230 | 0.58 | 0.79 | 32 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 1XQO · Crystal structure of native Pa-AGOG, 8-oxoguanine DNA glycosylase from Pyrobaculum… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8ZVK6 · AlphaFold monomer V2.0 prediction for N-GLYCOSYLASE/DNA lyase (Q8ZVK6) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZVK6
- Elsewhere: RCSB PDB 1XQO · PDBe 1XQO · UniProt Q8ZVK6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.