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Crystal structure of native pa-agog, 8-oxoguanine DNA glycosylase from pyrobaculum aerophilum

Analyse Crystal structure of native pa-agog, 8-oxoguanine DNA glycosylase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1XQO
Type: protein
Length: 253 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 8-oxoguanine DNA glycosylase
UniProt: Q8ZVK6
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	8-oxoguanine DNA glycosylase	protein	253	64% helix, 0% strand	Q8ZVK6

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	230	0.58	0.79	32	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

1XQO · Crystal structure of native Pa-AGOG, 8-oxoguanine DNA glycosylase from Pyrobaculum… · the same entry in another collection · chain A against A, TM-score 1.00
Q8ZVK6 · AlphaFold monomer V2.0 prediction for N-GLYCOSYLASE/DNA lyase (Q8ZVK6) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8ZVK6
Elsewhere: RCSB PDB 1XQO · PDBe 1XQO · UniProt Q8ZVK6

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