MolNFT v1 · #27203 · protein
Crystal structure of longer splice variant of PTD012 from homo sapiens reveals a novel zinc-containing fold
1XCR · Hypothetical protein PTD012: “Crystal structure of longer splice variant of PTD012 from homo sapiens reveals a novel zinc-containing fold”. X-ray diffraction, 1 ligand (ZN), 5 pockets (best druggability 0.71). MolNFT v1 #27203 on…
- PDB
- 1XCR
- Type
- protein
- Length
- 626 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein PTD012
- UniProt
- Q9H0W9
- Ligands
- ZN
- Pockets
- 5 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 17% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hypothetical protein PTD012 | protein | 313 | 17% helix, 41% strand | Q9H0W9 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.71 | 0.96 | 24 | ACY |
| 2 | 51 | 0.70 | 0.98 | 19 | ACY |
| 3 | 100 | 0.46 | 0.80 | 20 | empty |
| 4 | 78 | 0.38 | 0.78 | 15 | empty |
| 5 | 62 | 0.30 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 634 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 1XCR · Crystal Structure of Longer Splice Variant of PTD012 from Homo sapiens reveals a novel… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H0W9 · AlphaFold monomer V2.0 prediction for ester hydrolase C11ORF54 (Q9H0W9) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H0W9
- Elsewhere: RCSB PDB 1XCR · PDBe 1XCR · UniProt Q9H0W9
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