MolNFT v1 · #26920 · protein

Solution structure of dsrm domain in DGCR8 protein

1X47: “Solution structure of dsrm domain in DGCR8 protein”. Solution nmr, 1 pocket (best druggability 0.40). MolNFT v1 #26920 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1X47
Type: protein
Length: 98 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DGCR8 protein
UniProt: Q8WYQ5
Pockets: 1 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 30% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DGCR8 protein	protein	98	30% helix, 21% strand	Q8WYQ5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	127	0.40	0.74	18	empty

Compared structures

1X47 · Solution structure of DSRM domain in DGCR8 protein · the same entry in another collection · chain A against A, TM-score 1.00
Q8WYQ5 · AlphaFold monomer V2.0 prediction for microprocessor complex subunit DGCR8 (Q8WYQ5) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WYQ5
Elsewhere: RCSB PDB 1X47 · PDBe 1X47 · UniProt Q8WYQ5

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