MolNFT v1 · #26681 · protein

Crystal structure of conserved hypothetical protein TT2028 from an extremely thermophilic bacterium thermus thermophilus HB8

1WWM: “Crystal structure of conserved hypothetical protein TT2028 from an extremely thermophilic bacterium thermus…”. X-ray diffraction, 4 pockets (best druggability 0.78). MolNFT v1 #26681 on GenesisL1: 3D structure, binding sites and…

PDB: 1WWM
Type: protein
Length: 341 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein TT2028
UniProt: Q5SLX4
Pockets: 4 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein TT2028	protein	180	76% helix, 0% strand	Q5SLX4
B	Hypothetical protein TT2028	protein	161	78% helix, 0% strand	Q5SLX4

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	193	0.78	0.93	36	empty
2	240	0.67	0.83	26	empty
3	83	0.37	0.76	18	empty
4	50	0.28	0.75	11	empty

Interfaces

1 interface between chains.

A–B · 897 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

1WWM · Crystal Structure of Conserved Hypothetical Protein TT2028 from an Extremely Thermophilic… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SLX4
Elsewhere: RCSB PDB 1WWM · PDBe 1WWM · UniProt Q5SLX4

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