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Crystal structure of conserved hypothetical protein TT2028 from an extremely thermophilic bacterium thermus thermophilus HB8

Analyse Crystal structure of conserved hypothetical protein TT2028 from an extremely… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WWM
Type: protein
Length: 341 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein TT2028
UniProt: Q5SLX4
Pockets: 4 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein TT2028	protein	180	76% helix, 0% strand	Q5SLX4
B	Hypothetical protein TT2028	protein	161	78% helix, 0% strand	Q5SLX4

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	193	0.78	0.93	36	empty
2	240	0.67	0.83	26	empty
3	83	0.37	0.76	18	empty
4	50	0.28	0.75	11	empty

Interfaces

1 interface between chains.

A–B · 897 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

1WWM · Crystal Structure of Conserved Hypothetical Protein TT2028 from an Extremely Thermophilic… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SLX4
Elsewhere: RCSB PDB 1WWM · PDBe 1WWM · UniProt Q5SLX4

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