MolNFT v1 · #26669 · protein

Ngf binding domain of human trka receptor

1WWA · Protein (nerve growth factor receptor trka): “Ngf binding domain of human trka receptor”. X-ray diffraction. MolNFT v1 #26669 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WWA
Type: protein
Length: 210 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (nerve growth factor receptor trka)
UniProt: P04629

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 55% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Protein (nerve growth factor receptor trka)	protein	105	3% helix, 54% strand	P04629
Y	Protein (nerve growth factor receptor trka)	protein	105	3% helix, 56% strand	P04629

Interfaces

1 interface between chains.

X–Y · 2079 Å² buried · 37 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1WWA · Ngf binding domain of human trka receptor · the same entry in another collection · chain X against X, TM-score 1.00
P04629 · AlphaFold monomer V2.0 prediction for high affinity nerve growth factor receptor (P04629) · a predicted model of the same protein · chain X against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04629
Elsewhere: RCSB PDB 1WWA · PDBe 1WWA · UniProt P04629

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