MolNFT v1 · #26550 · protein

The solution structures of human orexin-a

1WSO: “The solution structures of human orexin-a”. Solution nmr, 1 ligand (NH2). MolNFT v1 #26550 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WSO
Type: protein
Length: 33 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Orexin-a
UniProt: O43612
Ligands: NH2

Structure

solution nmr · 1 distinct chain · 61% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Orexin-a	protein	33	61% helix, 0% strand	O43612

Ligands and binding sites

NH2 · Amino group · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 2 disulfide, 1 modified (disulfide, cyclization).

Compared structures

1WSO · The solution structures of human Orexin-A · the same entry in another collection · chain A against A, TM-score 1.00
O43612 · AlphaFold monomer V2.0 prediction for orexin (O43612) · a predicted model of the same protein · chain A against A, TM-score 0.33

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43612
Elsewhere: RCSB PDB 1WSO · PDBe 1WSO · UniProt O43612

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