MolNFT v1 · #26377 · protein
Crystal structure of archaeal family B DNA polymerase mutant
1WN7: “Crystal structure of archaeal family B DNA polymerase mutant”. X-ray diffraction, 1 ligand (NI), 13 pockets (best druggability 0.67). MolNFT v1 #26377 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1WN7
- Type
- protein
- Length
- 729 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Family B DNA polymerase
- EC
- 2.7.7.7
- Ligands
- NI
- Pockets
- 13 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Family B DNA polymerase (EC 2.7.7.7) | protein | 729 | 37% helix, 20% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
13 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 501 | 0.67 | 0.78 | 57 | empty |
| 2 | 216 | 0.53 | 0.77 | 23 | NI |
| 3 | 185 | 0.50 | 0.77 | 22 | empty |
| 4 | 142 | 0.49 | 0.78 | 26 | empty |
| 5 | 80 | 0.47 | 0.82 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1WN7 · Crystal structure of archaeal family B DNA polymerase mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1WN7 · PDBe 1WN7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.