MolNFT v1 · #26309 · protein
Mg-substituted form of E. COLI aminopeptidase P
1WL6 · Xaa-pro aminopeptidase: “Mg-substituted form of E. COLI aminopeptidase P”. X-ray diffraction, 2 ligands (MG, CL), 3 pockets (best druggability 0.51). MolNFT v1 #26309 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1WL6
- Type
- protein
- Length
- 440 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Xaa-pro aminopeptidase
- EC
- 3.4.11.9
- UniProt
- P15034
- Ligands
- MG, CL
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Xaa-pro aminopeptidase (EC 3.4.11.9) | protein | 440 | 41% helix, 19% strand | P15034 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · 2 copies · chains A
- IPA · Isopropyl alcohol · additive · 2 copies · chains A
- XPE · 3,6,9,12,15,18,21,24,27-nonaoxanonacosane-1,29-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 215 | 0.51 | 0.76 | 30 | empty |
| 2 | 83 | 0.40 | 0.78 | 20 | IPA |
| 3 | 50 | 0.25 | 0.74 | 14 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15034
- Elsewhere: RCSB PDB 1WL6 · PDBe 1WL6 · UniProt P15034
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.