XPE · 3,6,9,12,15,18,21,24,27-nonaoxanonacosane-1,29-diol

Binding sites

XPE in 19 structures; the first of them:

• 5TVY · Computationally Designed Fentanyl Binder - Fen49 · XPE A201 · binds TYR5, LEU7, PHE9, SER35, VAL37, TRP63, VAL69, TRP71 and 12 more
• 6EN5 · Crystal structure A of the Angiotensin-1 converting enzyme N-domain in complex with a… · XPE D724 · binds GLN286, GLY287, TRP288, HIS292, ARG295, VAL296, GLU299, ILE408 and 8 more
• 6GY4 · Crystal structure of the N-terminal KH domain of human BICC1 · XPE C203 · binds MET46, GLU48, GLN87, LYS107, SER109, GLU48, GLN87, ALA89 and 2 more
• 6H5X · Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with… · XPE A711 · binds GLN286, GLY287, TRP288, HIS292, ARG295, VAL296, ILE408
• 8QFX · Human Angiotensin-1 converting enzyme N-domain in complex with the lactotripeptide IPP · XPE A706 · binds PHE228, ARG231, ALA232, ARG235, ARG236, MET267, VAL268, VAL269 and 2 more
• 5TVY · Computationally designed fentanyl binder - FEN49 · XPE A201 · binds TYR5, LEU7, PHE9, SER35, TRP63, TRP71, TYR80, TRP90 and 6 more
• 6EN5 · Crystal structure a of the angiotensin-1 converting enzyme N-domain in complex with a… · XPE D724 · binds GLN286, GLY287, TRP288, HIS292, VAL296, GLU299, ILE408, GLN286 and 7 more
• 6EN6 · Crystal structure B of the angiotensin-1 converting enzyme N-domain in complex with a… · XPE B731 · binds GLN286, GLY287, TRP288, HIS292, VAL296, GLU299, ILE408
• 6GY4 · Crystal structure of the N-terminal kh domain of human BICC1 · XPE C203 · binds MET46, GLU48, GLN87, LYS107, SER109, GLU48, GLN87, ALA89 and 2 more
• 6H5X · Crystal structure of human angiotensin-1 converting enzyme N-domain in complex with… · XPE A711 · binds GLN286, GLY287, TRP288, HIS292, ARG295, VAL296, ILE408
• 6QS1 · Crystal structure of human angiotensin-1 converting enzyme N-domain in complex with bppb · XPE A710 · binds GLN286, GLY287, TRP288, HIS292, ARG295, VAL296, GLU299, ILE408
• 6TT4 · Crystal structure of 'RES_S2 mutant human angiotensin-1 converting enzyme N-domain in… · XPE A711 · binds GLN286, GLY287, TRP288, HIS292, VAL296, GLU299, ILE408
• 6YND · GAPDH purified from the supernatant of HEK293F cells: crystal form 1 of 4. · XPE A3001 · binds ASP127, ALA128, PRO129, MET130, ASN136, LEU144, LYS219
• 6YNE · GAPDH purified from the supernatant of HEK293F cells: crystal form 2 of 4. · XPE A401 · binds HIS165, ASP166, ASN167, PHE168, GLY169, GLU250, LYS251

Residues it binds most

LYS 33, ALA 34, PHE 30, ASN 32, PRO 32, GLY 22, MET 30, ASP 27, TRP 13, GLN 18 (residue and the binding sites it lines).

Found with

• CL · Chloride ion
• EDO · 1,2-ethanediol
• PGE · Triethylene glycol
• ZN · Zinc ion
• BMA · beta-D-mannopyranose
• FUC · alpha-L-fucopyranose
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• MG · Magnesium ion
• PEG · Di(hydroxyethyl)ether
• PG4 · Tetraethylene glycol
• ACT · Acetate ion
• BJ2 · (2~{S})-1-[(2~{S})-2-[[(1~{S})-1-[(2~{S})-1-[(2~{S})-2-azanyl-4-oxidanyl-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]-2-oxidanyl-2-oxidanylidene-ethyl]amino]propanoyl]pyrrolidine-2-carboxylic acid