MolNFT v1 · #26203 · protein
Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)
1WI0: “Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)”. Solution nmr, 1 pocket (best druggability 0.36). MolNFT v1 #26203 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1WI0
- Type
- protein
- Length
- 113 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mitogen activated protein kinase kinase 5
- EC
- 2.7.1.-
- UniProt
- Q9WVS7
- Pockets
- 1 · best druggability 0.36
Structure
solution nmr · 1 distinct chain · 28% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitogen activated protein kinase kinase 5 (EC 2.7.1.-) | protein | 113 | 28% helix, 20% strand | Q9WVS7 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.36 | 0.78 | 14 | empty |
Compared structures
- 1WI0 · Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9WVS7 · AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WVS7
- Elsewhere: RCSB PDB 1WI0 · PDBe 1WI0 · UniProt Q9WVS7
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