MolNFT v1 · #26166 · protein

Ra domain of guanine nucleotide exchange factor for RAP1

1WGY · Rap guanine nucleotide exchange factor 5: “Ra domain of guanine nucleotide exchange factor for RAP1”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1 #26166 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WGY
Type: protein
Length: 104 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Rap guanine nucleotide exchange factor 5
UniProt: Q92565
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 13% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rap guanine nucleotide exchange factor 5	protein	104	13% helix, 22% strand	Q92565

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.41	0.77	18	empty

Compared structures

1WGY · RA domain of guanine nucleotide exchange factor for Rap1 · the same entry in another collection · chain A against A, TM-score 1.00
Q92565 · AlphaFold monomer V2.0 prediction for rap guanine nucleotide exchange factor 5 (Q92565) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92565
Elsewhere: RCSB PDB 1WGY · PDBe 1WGY · UniProt Q92565

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