MolNFT v1 · #2588 · protein

Solution structure of apaf-1 card

1C15 · Apoptotic protease activating factor 1: “Solution structure of apaf-1 card”. Solution nmr, 1 pocket (best druggability 0.35). MolNFT v1 #2588 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1C15
Type: protein
Length: 97 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Apoptotic protease activating factor 1
UniProt: O14727
Pockets: 1 · best druggability 0.35

Structure

solution nmr · 1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Apoptotic protease activating factor 1	protein	97	69% helix, 0% strand	O14727

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.35	0.79	13	empty

Compared structures

1C15 · Solution structure of apaf-1 card · the same entry in another collection · chain A against A, TM-score 1.00
O14727 · AlphaFold monomer V2.0 prediction for apoptotic protease-activating factor 1 (O14727) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14727
Elsewhere: RCSB PDB 1C15 · PDBe 1C15 · UniProt O14727

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