MolNFT v1 · #2552 · protein
The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor
1BZX · Protein (trypsin): “The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor”. X-ray diffraction, 1 ligand (CA). MolNFT v1 #2552 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1BZX
- Type
- protein
- Length
- 280 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (trypsin); Protein (bovine pancreatic trypsin inhibitor)
- EC
- 3.4.21.4
- UniProt
- P35031, P00974
- Ligands
- CA
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Protein (trypsin) (EC 3.4.21.4) | protein | 222 | 9% helix, 37% strand | P35031 |
| I | Protein (bovine pancreatic trypsin inhibitor) | protein | 58 | 21% helix, 28% strand | P00974 |
Ligands and binding sites
- CA · Calcium ion · metal · chains E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- E–I · 675 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 1BZX · The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin… · the same entry in another collection · chain E against E, TM-score 1.00
- P35031 · AlphaFold monomer V2.0 prediction for trypsin-1 (P35031) · a predicted model of the same protein · chain E against A, TM-score 0.99
- P00974 · AlphaFold monomer V2.0 prediction for pancreatic trypsin inhibitor (P00974) · a predicted model of the same protein · chain I against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35031
- Every structure of UniProt P00974
- Elsewhere: RCSB PDB 1BZX · PDBe 1BZX · UniProt P35031 · UniProt P00974
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