MolNFT v1 · #25512 · protein
Streptavidin-fshpqnt
1VWA: “Streptavidin-fshpqnt”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #25512 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1VWA
- Type
- protein
- Length
- 257 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Streptavidin; Peptide ligand containing hpq
- UniProt
- P22629
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 4 distinct chains · 9% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Streptavidin | protein | 123 | 11% helix, 57% strand | P22629 |
| D | Streptavidin | protein | 121 | 8% helix, 56% strand | P22629 |
| M | Peptide ligand containing hpq | protein | 6 | 0% helix, 0% strand | — |
| P | Peptide ligand containing hpq | protein | 7 | 0% helix, 0% strand | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 86 | 0.36 | 0.76 | 21 | empty |
Interfaces
3 interfaces between chains.
- B–D · 1618 Ų buried · 26 hydrogen bonds · protein-protein
- D–P · 461 Ų buried · 7 hydrogen bonds · protein-protein
- B–M · 404 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 1VWA · Streptavidin-fshpqnt · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22629
- Elsewhere: RCSB PDB 1VWA · PDBe 1VWA · UniProt P22629
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