MolNFT v1 · #25369 · protein

Phospholipase A2 inhibitor from vipoxin

1VPI: “Phospholipase A2 inhibitor from vipoxin”. X-ray diffraction, 1 pocket (best druggability 0.47). MolNFT v1 #25369 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1VPI
Type: protein
Length: 122 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phospholipase A2 inhibitor
UniProt: P04084
Pockets: 1 · best druggability 0.47

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phospholipase A2 inhibitor	protein	122	48% helix, 8% strand	P04084

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.47	0.79	23	empty

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

1VPI · Phospholipase A2 inhibitor from vipoxin · the same entry in another collection · chain A against A, TM-score 1.00
P04084 · AlphaFold monomer V2.0 prediction for acidic phospholipase A2 homolog vipoxin a chain… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04084
Elsewhere: RCSB PDB 1VPI · PDBe 1VPI · UniProt P04084

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.