MolNFT v1 · #25284 · protein

Crystal structure of 6-phosphogluconolactonase (TM1154) from thermotoga maritima at 1.70A resolution

1VL1: “Crystal structure of 6-phosphogluconolactonase (TM1154) from thermotoga maritima at 1.70A resolution”. X-ray diffraction, 2 pockets (best druggability 0.55). MolNFT v1 #25284 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1VL1
Type: protein
Length: 218 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 6-phosphogluconolactonase
EC: 3.1.1.31
UniProt: Q9X0N8
Pockets: 2 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	6-phosphogluconolactonase (EC 3.1.1.31)	protein	218	37% helix, 23% strand	Q9X0N8

Ligands and binding sites

CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	180	0.55	0.80	31	CIT
2	69	0.41	0.79	13	empty

Compared structures

1VL1 · Crystal structure of 6-phosphogluconolactonase (TM1154) from Thermotoga maritima at 1.70A… · the same entry in another collection · chain A against A, TM-score 1.00
Q9X0N8 · AlphaFold monomer V2.0 prediction for 6-phosphogluconolactonase (Q9X0N8) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X0N8
Elsewhere: RCSB PDB 1VL1 · PDBe 1VL1 · UniProt Q9X0N8

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