MolNFT v1 · #24972 · protein + RNA

Crystal structure of the hepatitis delta virus gemonic ribozyme precursor, with C75U mutaion, in edta solution

1VBX · Hepatitis delta virus ribozyme: “Crystal structure of the hepatitis delta virus gemonic ribozyme precursor, with C75U mutaion, in edta solution”. X-ray diffraction, 4 pockets (best druggability 0.63). MolNFT v1 #24972 on GenesisL1…

PDB: 1VBX
Type: protein + RNA
Length: 168 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hepatitis delta virus ribozyme; U1 small nuclear ribonucleoprotein a
UniProt: P09012
Pockets: 4 · best druggability 0.63

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Hepatitis delta virus ribozyme	rna	73	—	—
A	U1 small nuclear ribonucleoprotein a	protein	95	32% helix, 25% strand	P09012

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	445	0.63	0.78	35	empty
2	453	0.56	0.74	27	empty
3	285	0.48	0.73	17	empty
4	95	0.38	0.77	12	empty

Interfaces

1 interface between chains.

B–A · 953 Å² buried · 32 hydrogen bonds · protein-nucleic

Compared structures

1VBX · Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U… · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09012
Elsewhere: RCSB PDB 1VBX · PDBe 1VBX · UniProt P09012

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.