MolNFT v1 · #24758 · protein
Crystal structure of pyruvate oxidase containing FAD, from aerococcus viridans
1V5E: “Crystal structure of pyruvate oxidase containing FAD, from aerococcus viridans”. X-ray diffraction, 2 ligands (FAD, SO4), 4 pockets (best druggability 0.74). MolNFT v1 #24758 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1V5E
- Type
- protein
- Length
- 590 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pyruvate oxidase
- EC
- 1.2.3.3
- Ligands
- FAD, SO4
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyruvate oxidase (EC 1.2.3.3) | protein | 590 | 41% helix, 16% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 785 | 0.74 | 0.79 | 67 | FAD |
| 2 | 144 | 0.62 | 0.85 | 27 | empty |
| 3 | 81 | 0.58 | 0.87 | 23 | SO4 |
| 4 | 81 | 0.57 | 0.87 | 21 | empty |
Compared structures
- 1V5E · Crystal Structure of Pyruvate oxidase containing FAD, from Aerococcus viridans · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1V5E · PDBe 1V5E
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