MolNFT v1 · #24381 · protein

Pig purple acid phosphatase complexed with phosphate

1UTE · Protein (II purple acid phosphatase): “Pig purple acid phosphatase complexed with phosphate”. X-ray diffraction, 3 ligands (FEO, NAG, PO4), 2 pockets (best druggability 0.33). MolNFT v1 #24381 on GenesisL1: 3D structure, binding…

PDB: 1UTE
Type: protein
Length: 302 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (II purple acid phosphatase)
EC: 3.1.3.2
UniProt: P09889
Ligands: FEO, NAG, PO4
Pockets: 2 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (II purple acid phosphatase) (EC 3.1.3.2)	protein	302	27% helix, 24% strand	P09889

Ligands and binding sites

FEO · Mu-oxo-diiron · ligand · chains A
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
PO4 · Phosphate ion · ion · chains A
IPA · Isopropyl alcohol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.33	0.76	14	empty
2	55	0.30	0.76	17	PO4

Modifications

Observed in the structure: 1 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

1UTE · Pig purple acid phosphatase complexed with phosphate · the same entry in another collection · chain A against A, TM-score 1.00
P09889 · AlphaFold monomer V2.0 prediction for tartrate-resistant acid phosphatase type 5 (P09889) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09889
Elsewhere: RCSB PDB 1UTE · PDBe 1UTE · UniProt P09889

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