MolNFT v1 · #24250 · protein

UP1, the two RNA-recognition motif domain of hnrnp A1

1UP1 · Heterogeneous nuclear ribonucleoprotein A1: “UP1, the two RNA-recognition motif domain of hnrnp A1”. X-ray diffraction, 1 pocket (best druggability 0.48). MolNFT v1 #24250 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1UP1
Type: protein
Length: 170 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heterogeneous nuclear ribonucleoprotein A1
UniProt: P09651
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heterogeneous nuclear ribonucleoprotein A1	protein	170	24% helix, 36% strand	P09651

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.48	0.81	21	empty

Compared structures

1UP1 · UP1, the two RNA-recognition motif domain of hnrnp A1 · the same entry in another collection · chain A against A, TM-score 1.00
P09651 · AlphaFold monomer V2.0 prediction for heterogeneous nuclear ribonucleoprotein A1 (P09651) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09651
Elsewhere: RCSB PDB 1UP1 · PDBe 1UP1 · UniProt P09651

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.