MolNFT v1 · #23519 · protein

Structure cbp TAZ1 domain

1U2N · Creb binding protein: “Structure cbp TAZ1 domain”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.41). MolNFT v1 #23519 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1U2N
Type: protein
Length: 100 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Creb binding protein
EC: 2.3.1.48
UniProt: P45481
Ligands: ZN
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 61% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Creb binding protein (EC 2.3.1.48)	protein	100	61% helix, 0% strand	P45481

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	112	0.41	0.76	17	empty

Compared structures

1U2N · Structure CBP TAZ1 Domain · the same entry in another collection · chain A against A, TM-score 1.00
P45481 · AlphaFold monomer V2.0 prediction for histone lysine acetyltransferase crebbp (P45481) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P45481
Elsewhere: RCSB PDB 1U2N · PDBe 1U2N · UniProt P45481

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