MolNFT v1 · #23426 · protein

T. maritima nusb, P3221

1TZX · N utilization substance protein B homolog: “T. maritima nusb, P3221”. X-ray diffraction, 4 pockets (best druggability 0.63). MolNFT v1 #23426 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1TZX
Type: protein
Length: 282 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: N utilization substance protein B homolog
UniProt: Q9X286
Pockets: 4 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	N utilization substance protein B homolog	protein	141	72% helix, 0% strand	Q9X286

Ligands and binding sites

CIT · Citric acid · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	359	0.63	0.78	25	CIT
2	161	0.57	0.81	23	empty
3	54	0.33	0.77	13	empty
4	53	0.32	0.77	16	empty

Interfaces

1 interface between chains.

A–B · 592 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

1TZX · T. maritima NusB, P3221 · the same entry in another collection · chain A against A, TM-score 1.00
Q9X286 · AlphaFold monomer V2.0 prediction for transcription antitermination protein nusb (Q9X286) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X286
Elsewhere: RCSB PDB 1TZX · PDBe 1TZX · UniProt Q9X286

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