MolNFT v1 · #23361 · protein

Active-site variant of E.COLI thioredoxin

1TXX · Protein (thioredoxin): “Active-site variant of E.COLI thioredoxin”. X-ray diffraction, 1 ligand (CU). MolNFT v1 #23361 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1TXX
Type: protein
Length: 108 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (thioredoxin)
EC: 1.8.-.-
UniProt: P0AA25
Ligands: CU

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (thioredoxin) (EC 1.8.-.-)	protein	108	32% helix, 28% strand	P0AA25

Ligands and binding sites

CU · Copper (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1TXX · Active-site variant of E.COLI thioredoxin · the same entry in another collection · chain A against A, TM-score 1.00
P0AA25 · AlphaFold monomer V2.0 prediction for thioredoxin 1 (P0AA25) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AA25
Elsewhere: RCSB PDB 1TXX · PDBe 1TXX · UniProt P0AA25

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