MolNFT v1 · #23112 · protein

Non-covalent swapped dimer of bovine seminal ribonuclease in complex with 2'-deoxycytidine-2'-deoxyadenosine-3',5'- monophosphate

1TQ9 · Ribonuclease, seminal: “Non-covalent swapped dimer of bovine seminal ribonuclease in complex with…”. X-ray diffraction, 1 ligand (CPA). MolNFT v1 #23112 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1TQ9
Type: protein
Length: 248 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonuclease, seminal
EC: 3.1.27.5
UniProt: P00669
Ligands: CPA

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Ribonuclease, seminal (EC 3.1.27.5)	protein	124	21% helix, 37% strand	P00669

Ligands and binding sites

CPA · 2'-deoxycytidine-2'-deoxyadenosine-3',5'-monophosphate · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 2067 Å² buried · 43 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide, 4 modified (disulfide, alkylation).

Compared structures

1TQ9 · Non-covalent swapped dimer of Bovine Seminal Ribonuclease in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
P00669 · AlphaFold monomer V2.0 prediction for seminal ribonuclease (P00669) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00669
Elsewhere: RCSB PDB 1TQ9 · PDBe 1TQ9 · UniProt P00669

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